Compile Data Set for Download or QSAR
Found 388 from University of Iowa
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50159165((2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(fura...)copy SMILEScopy InChI
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343253(CHEMBL1773748 | Dimethyl 5-((2S,4aR,6aR,7R,9S,10aS...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343252(CHEMBL1773747 | Diethyl 5-((2S,4aR,6aR,7R,9S,10aS,...)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343257(CHEMBL1773752 | Diethyl 4-((2S,4aR,6aR,7R,9S,10aS,...)copy SMILEScopy InChI
Affinity DataKi:  228nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343250(CHEMBL1773753 | Dimethyl 4-((2S,4aR,6aR,7R,9S,10aS...)copy SMILEScopy InChI
Affinity DataKi:  286nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343256((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-2-(8...)copy SMILEScopy InChI
Affinity DataKi:  290nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343254((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-2-(7...)copy SMILEScopy InChI
Affinity DataKi:  790nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343256((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-2-(8...)copy SMILEScopy InChI
Affinity DataKi: >1.70E+3nMAssay Description:Agonist activity at mu opioid receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343252(CHEMBL1773747 | Diethyl 5-((2S,4aR,6aR,7R,9S,10aS,...)copy SMILEScopy InChI
Affinity DataKi:  2.26E+3nMAssay Description:Displacement of [3H]DADLE from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343254((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-2-(7...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+3nMAssay Description:Agonist activity at mu opioid receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343255((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-2-(8...)copy SMILEScopy InChI
Affinity DataKi: >2.70E+3nMAssay Description:Agonist activity at mu opioid receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343251((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-6a,1...)copy SMILEScopy InChI
Affinity DataKi: >3.00E+3nMAssay Description:Agonist activity at mu opioid receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343250(CHEMBL1773753 | Dimethyl 4-((2S,4aR,6aR,7R,9S,10aS...)copy SMILEScopy InChI
Affinity DataKi: >3.00E+3nMAssay Description:Agonist activity at mu opioid receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343257(CHEMBL1773752 | Diethyl 4-((2S,4aR,6aR,7R,9S,10aS,...)copy SMILEScopy InChI
Affinity DataKi: >3.00E+3nMAssay Description:Agonist activity at mu opioid receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343252(CHEMBL1773747 | Diethyl 5-((2S,4aR,6aR,7R,9S,10aS,...)copy SMILEScopy InChI
Affinity DataKi: >3.20E+3nMAssay Description:Agonist activity at mu opioid receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343253(CHEMBL1773748 | Dimethyl 5-((2S,4aR,6aR,7R,9S,10aS...)copy SMILEScopy InChI
Affinity DataKi: >4.80E+3nMAssay Description:Agonist activity at mu opioid receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343256((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-2-(8...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DADLE from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343253(CHEMBL1773748 | Dimethyl 5-((2S,4aR,6aR,7R,9S,10aS...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DADLE from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343250(CHEMBL1773753 | Dimethyl 4-((2S,4aR,6aR,7R,9S,10aS...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DADLE from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343251((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-6a,1...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DADLE from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343257(CHEMBL1773752 | Diethyl 4-((2S,4aR,6aR,7R,9S,10aS,...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DADLE from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343255((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-2-(8...)copy SMILEScopy InChI
Affinity DataKi: >5.20E+3nMAssay Description:Displacement of [3H]DADLE from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343251((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-6a,1...)copy SMILEScopy InChI
Affinity DataKi: >8.00E+3nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50159165((2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(fura...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DADLE from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343254((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-2-(7...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DADLE from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50343255((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-2-(8...)copy SMILEScopy InChI
Affinity DataKi: >1.30E+4nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W9VPubMed
TargetAmine oxidase [flavin-containing] B(Bos taurus)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50012278((2ALPHA,2''BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLAS...)copy SMILEScopy InChI
Affinity DataKi:  7.70E+4nMAssay Description:Inhibitory activity of the compound against Monoamine oxidase B isolated from beef liver mitochondria was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9NCDPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50368271(CHEMBL1204112)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of FDPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of FDPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of FDPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of FDPS (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human receptor-interacting serine-threonine kinase 2 (RIPK2) at 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56J8XPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50273716(CHEMBL457423 | [2-(Benzoimidazol-1-yl)ethyl]-bisph...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DW5PubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit hydrolytic activity of Acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of Mitogen-activated protein kinase 14 (P38 alpha) at 100 uM ATPMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50151859(CHEMBL3775876)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as radiolabeled GGPP formation preincubated for 10 mins followed by addition of 10 uM FPP s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B04DNPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50452817(CHEMBL4203457)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098JKPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50452817(CHEMBL4203457)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8HH6PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50452820(CHEMBL4204129)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098JKPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50031853(((3E,7E)-4,8,12-Trimethyl-1-phosphono-trideca-3,7,...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of GST-tagged human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37PPPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50452821(CHEMBL4208809)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098JKPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50031853(((3E,7E)-4,8,12-Trimethyl-1-phosphono-trideca-3,7,...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB17RNPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50452821(CHEMBL4208809)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098JKPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50272016(CHEMBL4130153)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of Escherichia coli DNA gyrase subunit GyrA/GyrB supercoiling activity using relaxed pBR322 DNA incubated for 15 mins by ethidium bromide ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9DJ0PubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50272019(CHEMBL4127152)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of Escherichia coli DNA gyrase subunit GyrA/GyrB supercoiling activity using relaxed pBR322 DNA incubated for 15 mins by ethidium bromide ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9DJ0PubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50205450((S)-7-(3-(aminomethyl)pyrrolidin-1-yl)-1-cycloprop...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as supercoiling activity by fluorescence assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PFFPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50272016(CHEMBL4130153)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of Escherichia coli DNA gyrase subunit GyrA/GyrB supercoiling activity using relaxed pBR322 DNA incubated for 15 mins by ethidium bromide ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9DJ0PubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 124nMAssay Description:Inhibition of human casein kinase 1 delta at 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56J8XPubMed
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